Bacteria “flow on the stomach lining” could indicate the risk of gastric cancer, the new study finds

In recent years, studies have suggested that gastric microbiome can play a role in the development of cancer. However, these studies had no data on the place where bacteria are located in the stomach.

Using the latest imaging technology to identify the location of bacteria, scientists could see that while H. pylori Gastric glands colonized exclusively, non-H. pylori Bacteria have leaked through the lining of the stomach under pre-cancer conditions, gastric intestinal metaplasia. These discoveries suggest that bacterial leakage in deeper gastric tissues can be a previous factor overlooked in cancer progression.

Researchers say that discovery can explain and why only a minority of H. pylori Infections lead to gastric cancer and could open the way for innovative diagnostic and therapeutic approaches.

The correspondent author of the work Dr. Amanda Rossiter-Pearson of the University of Birmingham said:

“We are delighted by the potential of this observation to open a new research way in preventing stomach cancer. A simple antibiotic treatment may be used to treat these bacteria. However, there is much more work to do.

“We must first determine the identity of these bacteria and understand how the presence of these bacteria in the precancerous state has an impact on the patient’s risk of developing stomach cancer.“

Dr. Talisia Quallo, Cancer Research UK research schedule, said:

“Stomach cancer has limited treatment options and weak survival rates. Better approaches are needed to find it earlier and to provide treatment when it is more likely to be successful.

“This research shows us that the most common type of bacteria related to stomach cancer, Helicobacter Pylori, can work alongside other bacteria to lead a precursor condition to stomach cancer. It takes a lot more research to understand how this interaction works and what they could do to stop it, but from this research we can explore new ways to detect who will continue to develop stomach cancer. “