The new synthetic bone graft can have a fusion rate of the higher spine compared to bone autographs

Key charges:

• A new synthetic bone graft has shown non -inferiority to autograph in the fusion of the posterolateral spine.
• Also, the synthetic graft has diminished the effects of smoking on surgical results.

San Diego – a novel synthetic bone graft Using biphasic calcium phosphate in the form of submicron can be superior to bone autographs for instrumental posterolaterals the fusion of the spineAccording to the results presented here.

Robert K. Eastlack, Md, faaos, The head of the Surgery Surgery Division at the Scripps clinic in La Jolla, California, And colleagues have registered 100 patients indicated for fusion of the posterolateral spine of one to six levels from T10-S2 in a prospect randomized control study To compare the surgical effectiveness of a new advanced synthetic bone graft (Magnetos, Kuros Biosciences) compared to an bone autograph with an iliac ridge greater than 50%.

Patients were randomly distributed a synthetic bone graft to one side and a bone autograph on the contralateral side, Eastlack said in its presentation at the annual meeting of the American Academy of Orthopedic surgeons.

Robert K. Eastlack

The main result of the study was the merger rate, which was measured using CT evaluations. Eastlack and colleagues also collected results reported results.

According to Eastlack, the fusion rate with the synthetic graft was about 80% compared to about 50% with the bone autograph.

In addition, he said that patients who were smokers have a fusion rate of approximately 75% with synthetic graft compared to about 30% with the bone autograph.

“There is a clear benefit of this material on the iliac ridge, which was considered the anterior gold standard in a posterolateral fusion model,” said Eastlack.

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Sources/disclosures

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Source: Eastlack RK et al. Document 303. March 10-14, 2025; San Diego.

Disclosures: Eastlack reports that receive research and consulting assistance fees at Kuros Biosciences.

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